When you enter your room, place your suitcase/belongings in the bathroom & hang up your coat instead of placing things on your bed at first.
We also highly recommend that you do a quick overall inspection of the bed & even headboard. By this we mean “un-tuck” the corners of the bed & check the mattress, especially in the corners. You probably won’t see the bugs, but you just might see eggs (yuck) – dead shredded skins and there might even be a slight odor (raspberry). Don’t be shy to complain & insist on changing rooms. In my experience, most Hotels are willing to accommodate your needs.
And finally, when you return home, open your luggage in your garage & wash your travel clothes immediately!